Effect of HIIT and MIT on TNF-α levels and blood profile for obesity therapy

Study purpose. Discusses the outcomes of Moderate Intensity Training (MIT) and High Interval (HIIT) on Tumor Necrosis Factor-alpha (TNF-α) blood profiles to be used as a treatment option for obesity. Material Methods. This research is true experimental laboratory with post-test-only control group design. Using 39 obese male Wistar rats distribution 13 HIIT groups, MIT, control. The exercise intervention consists intensity (90–100% baseline ability), MIT (60-80% without training six weeks. A specialized rat treadmill was exercises. Measuring TNF-α levels an enzyme-linked immunosorbent assay (ELISA). Hematology test determine eritrosit, leukosit, trombosit. Data analysis Anova test. Result. in were significantly higher than levels, indicated by P values 0.003 (HIIT vs Control) 0.001 (MIT Control). There weren’t any big differences. tests erythrocytes, leukocytes, platelets between groups. At body weight, lower = 0.000, also 0.002. Conclusion. Exercise 6 weeks can alternative overcome obesity because it reduce weight obesity, but not accompanied decrease platelets.